Ditto. (Powell's is the book store.) We were supposed to do a PDX weekend trip a couple years back but it kept getting postponed due to work craziness. I actually had a spreadsheet of breweries I wanted to hit, but I must have finally deleted it. I know Hopworks Urban Brewery (HUB), Ninkasi, and Laurelwood were ones I was really looking forward to.
We loved the Classical Chinese Garden. Voodoo donuts (that only partially counts as food, that's a landmark!). We went on a walking tour that was about 2 hours, billed as learning about the "shady side" of ghosts and prostitutes of early Portland but I guess it depends on the guide as ours downplayed all that as much as he was able, but learning about the early history of Portland and cool architecture was neat. Then again, we're nerds