16x20 to keep it more uniform for mat size. But take this with a grain of salt because everything that I have matted was for studio / show use so we have 4" + of mat border or an 8x10 on the top half of a 16x32.
I prefer the look of a healthy border around my photos, I feel like it really shows of the image well.
16x20. I like thick mats or now mats at all. Plus I like the look of a big frame with two smaller frames on either side. We have a photo collage just like that in our dining room.