For those of you who take Zoloft (or another SSRI)...

[woodgnome]

If you miss a dose, what kind of symptoms do you have the next day? It really seems to affect me if I forget to take it. I forgot it last night and today, I feel short tempered, irritable, sluggish and generally just off. Plus brain zaps ugh

[ohgillian]

One dose no impact for me. 2 doses brain zaps.

[katfco]

When I was on a higher dose, I did notice if I missed even a day. By the end of the day, I might feel really irritable.

[woodgnome]

Jun 7, 2019 18:02:54 GMT -5 katfco said:

When I was on a higher dose, I did notice if I missed even a day. By the end of the day, I might feel really irritable.

I take 100 mg. I feel fine in the morning and then by midday I just feel like I want to jump out of my skin. I take it in the evening so I probably start feeling the effects 14-16 hours after missing the dose

[jezebel]

One day, I have numb lips and some brain zaps.

[revolution]

DH takes zoloft and he definitely knows he missed one dose. He will get headaches and "feel off"

[TrickyBob]

I take lexapro. If I miss one dose, no change. If I miss 2 or more, I start getting sick. Headaches, blurry vision, sick to my stomach.

[irishbride2]

Celexa

I swear if I’m even late I feel it. I feel irritable

Once I had a stomach bug and was puking constantly. I ended up going 48 hours without meds. I was a mess and sobbing non stop.

[picaflora]

I didn't notice after missing one dose, but I'm only on 50mg (for now). I haven't gone longer than missing just one dose though.

[Bernadine]

Cymbalta, and I get really dizzy.

[klingklang77]

I took Effexor, which is an SNRI like Cymbalta. I missed a dose two days in a row and wound up passing up on public transport and then had heart palpitations. I wound up in the hospital. From then on I decided that I didn’t want to be on these meds anymore and asked the doctor at the hospital how to do it. He said I could get off of it in a week. I did two weeks and I have had withdrawals for almost two years. They are getting better, but some days are too much.

If you decide to get off of them, really read up on how to. The doctors I had had no clue what to do with me.

[cjcouple]

I think it depends on the half life of the med. I know Prozac has a longer half life (3-6 days) than Zoloft (24 hours of I remember correctly) so a missed dose or Prozac shouldn't affect my son according to the Pedi. But we just started a few weeks ago and haven't missed one yet so not sure.

[hulley]

Zoloft, 100mg. I feel off day one, by it usually isn’t until day 2 (2nd missed dose) that I realize why.

I’m irritable, short tempered and I start to speak much faster.

What’s a “brain zap?”

[woodgnome]

Jun 8, 2019 10:58:09 GMT -5 hulley said:

Zoloft, 100mg. I feel off day one, by it usually isn’t until day 2 (2nd missed dose) that I realize why.

I’m irritable, short tempered and I start to speak much faster.

What’s a “brain zap?”

It feels like your brain was shocked. It’s terrible

[klingklang77]

Jun 8, 2019 15:19:06 GMT -5 woodgnome said:

Jun 8, 2019 10:58:09 GMT -5 hulley said:

Zoloft, 100mg. I feel off day one, by it usually isn’t until day 2 (2nd missed dose) that I realize why.

I’m irritable, short tempered and I start to speak much faster.

What’s a “brain zap?”

It feels like your brain was shocked. It’s terrible

Yes, it feels like your head was in a paint mixer. 

[jorja]

Irritability for sure. I’m on 20 mg of Lexapro and I notice the impact of one missed dose.

[lyssbobiss, Command, B613]

I take Effexor at night and if I forget or miss a dose, by about lunch the next day, I get brain zaps and weird lip numbness. Effexor and Zoloft have been the worst for the withdrawal symptoms for me - no other anti-depressant fucks me up quite as much.