More than a third of malaria drugs examined by scientists in Southeast Asia were fake, and a similar proportion analysed in Africa were below standard, doctors warned on Tuesday. "These findings are a wake-up call demanding a series of interventions to better define and eliminate both criminal production and poor manufacturing of antimalarial drugs," said Joel Breman of the Fogarty International Center at the US National Institutes of Health (NIH).
Trawling through surveys and published literature, the researchers found that in seven Southeast Asian countries, 36 percent of 1,437 samples, from five categories of drugs were counterfeit.
Thirty-percent of the samples failed a test of their pharmaceutical ingredients.
In 21 sub-Saharan countries, 20 percent of more than 2,500 samples tested in six drug classes turned out to be falsified, and 35 percent were below pharmaceutical norms.
Sub-standard medications are a major problem in the fight against malaria, a disease which killed 655,000 people in 2010, according to the UN's World Health Organisation (WHO).
Many of the drugs that are being faked or poorly manufactured are artemisin derivatives, the study said.
This is a special worry, for artemisinins are the frontline treatment for malaria, replacing drugs to which the malaria parasite has become resistant.
The study says there are many causes for the problem, ranging from widespread self-prescription of drugs to shoddy controls to monitor drug quality and prosecute counterfeiters.
"Poor-quality antimalarial drugs are very likely to jeopardise the unprecedented progress and investments in control and elimination of malaria made in the past decade," said Breman.
Last month, the Institute of Health Metrics and Evaluation at the University of Washington in Seattle reported that artemisin-resistant malaria which was first spotted in Cambodia in 2006 has since surged 800 kilometers (500 miles) westward to the Thailand-Myanmar border.
That's frightening, but not surprising. A friend of mine had to get a rbies shot in a remote area of India and she said in hindsight there was no way it was real (she works in medicine so she may know).
Im ridiculously paranoid about vaccinations, meds etc, I'm not chancing it!
Malarone is dirt cheap in Cambodia, which I took to mean is that it's fake.
Here in KL only a handful of pharmacies carry malaria medication at all and the price is on par with what it is in the US. I'm just going to stick my head in the sand and hope that means it's the real deal.
It is cheap in Laos too and some backpackers we met said they bought it there and both dh and I were skeptical afterwards that it was actually real, which would freak me out because I am terrified of malaria. I know someone who contacted it twice in Africa while working there and she used to leave notes for her family at night because she was certain she would be dead by morning.